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Bio-Rad Adds New PrimePCR™ Products for Droplet Digital™ PCR


Hercules, CA — March 2, 2015 — Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) today announced the launch of new PrimePCR Droplet Digital PCR (ddPCR™) Assays. This release expands Bio-Rad’s offering of predesigned validated copy number assays to a total of 658 targets, 57 of which are centromeric reference assays. The mutation detection assay offering now covers 209 mutations, of which 184 have short amplicon assays available for use with fragmented and challenging samples. This expansion also introduces assays for transcriptome-wide gene expression analysis of human, mouse, and rat genomes. In total, Bio-Rad now offers more than 120,000 PrimePCR Assays for use with Droplet Digital PCR.

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What is Droplet Digital™ PCR?


Droplet Digital PCR (ddPCR™) is Bio-Rad's unique digital PCR technology. With unrivaled precision, ddPCR provides absolute quantification of target DNA or RNA molecules without the use of standard curves. ddPCR addresses the lack of scalable and practical technologies for digital PCR implementation. The QX200™ ddPCR System puts this powerful technology in your hands, ready to unveil new worlds of research at previously unattainable levels.

Download the Droplet Digital PCR Applications Guide for in-depth information about setting up experiments.

Download the Droplet Digital PCR Applications Guide for in-depth information about setting up experiments.

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ddPCR™ KRAS Screening Multiplex Kit for Cancer Research


The ddPCR KRAS Screening Multiplex Kit allows detection of seven of the most common KRAS mutations in a single ddPCR experiment.

Hercules, CA — January 12, 2015 — Bio-Rad Laboratories, Inc. (NYSE: BIO and BIOb) today announced the launch of the ddPCR™ KRAS Screening Multiplex Kit, the latest offering in the company’s Droplet Digital™ PCR line of predesigned, fully wet-lab validated assays. The ddPCR KRAS Screening Multiplex Kit offers improved sensitivity and simultaneous detection of the seven most common KRAS mutations in a single ddPCR experiment.

KRAS mutations are found in 90% of pancreatic cancer cases and 30% of colorectal cancer cases, making it a gene of great interest to cancer researchers. The Multiplex Kit is able to detect and quantify extremely low levels (down to 0.2%) of KRAS mutant DNA in a single assay. Cancer samples are often available in limited quantities. Using the Multiplex Kit, researchers can derive results from low amounts of starting material.

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QX200™ AutoDG™ Droplet Digital™ PCR System


The QX200 AutoDG Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules for EvaGreen and probe-based Droplet Digital PCR (ddPCR™) applications. The Automated Droplet Generator simplifies the ddPCR workflow, making digital PCR both scalable and practical.

The AutoDG Instrument eliminates user-to-user variability, allowing you to fully exploit the precision of ddPCR technology by providing more consistent droplet counts across users and plates. The AutoDG Instrument also minimizes hands-on time — it takes less than 5 minutes to load the instrument, and no supervision or user activity is required during droplet generation.

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